From Morning Prayer:
"You shall seek the Lord, your God; and you shall indeed find him when you search after him with your whole heart and your whole soul." (Dt 4:29)
I find comfort knowing that my efforts are guaranteed to be fruitful, as long as I don't hold back any part of my life from God.
For me, the challenge there is letting go of my daily desire to be in control: to have everything run smoothly, to get X Y and Z accomplished, to have obedient toddlers (oxymoron), to have a little time to myself. So I'm working on having a plan, but not holding on to it too tightly. Leaving wiggle room for the Spirit.